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− | * The Nobel Peace Prize 2019 was awarded to Ethiopian President Abiy Ahmed Ali for his efforts to achieve peace and international cooperation. <small>([[Ethiopia#October_11|more]])</small> [[File:Ethiopia.gif]] | + | * French, Swiss and Moroccan researchers have discovered the remains of now-extinct creatures called trilobites. <small>([[France#October_17|more]])</small> [[File:France.gif]] [[File:Switzerland.gif]] [[File:Morocco.gif]] |
− | * The Nobel Prize in Literature was awarded to Peter Handke of Austria for an influential work that with linguistic ingenuity has explored the periphery of human experience. <small>([[Austria#October_10|more]])</small> [[File:Austria.gif]]
| + | * Brazil won a seat on the United Nations Human Rights Council for three-year terms starting in January <small>([[Brazil#October_17|more]])</small> [[File:Brazil.gif]] |
− | * Japanese scientists Akira Yoshino won the Nobel Prize in Chemistry 2019 for the development of lithium-ion batteries. <small>([[Japan#October_9|more]])</small> [[File:Japan.gif]]
| + | * Bonita Sharma of Nepal was named on BBC 100 Inspiring and Influential Women from around the world for 2019. <small>([[Nepal#October_16|more]])</small> [[File:Nepal.gif]] |
− | * Swiss and Canadian scientists were awarded the Nobel Prize in Physics for ground-breaking discoveries about the evolution of the universe. <small>([[Switzerland#October_8|more]])</small> [[File:Switzerland.gif]] [[File:Canada.gif]] | + | * The World Economic Forum rated Singapore as the world's most economically competitive country. <small>([[Singapore#October_9|more]])</small> [[File:Singapore.gif]] |
− | * The 2019 Nobel Prize in Medicine was awarded to English and American scientists for their discoveries of how cells adapt to oxygen availability. <small>([[England#October_7|more]])</small> [[File:England.gif]] [[File:United_States.gif]] | + | * A rare, expressive image of a fox attacking a marmot won Chinese photographer Yongqing Bao the prestigious 2019 Wildlife Photographer of the Year award. <small>([[China#October_15|more]])</small> [[File:China.gif]] |
− | * Venezuelan athlete Yulimar Rojas retained her world triple jump title with a huge jump of 15.37 meters at the World Athletics Championships. <small>([[Venezuela#October_5|more]])</small> [[File:Venezuela.gif]] | + | * A trio of Americans, Abhijit Banerjee, Esther Duflo and Michael Kremer, won the 2019 Nobel Economics Prize for their work in the fight against poverty. <small>([[United_States#October_14|more]])</small> [[File:United_States.gif]] |
− | * Canadian researchers have discovered what they believe is a novel drug target controlling the body’s repair responses after a heart attack. <small>([[Canada#October_3|more]])</small> [[File:Canada.gif]] | + | * Kenyan long-distance runner Eliud Kipchoge created history by becoming the first athlete to run a marathon in under two hours. <small>([[Kenya#October_12|more]])</small> [[File:Kenya.gif]] |
− | * Israeli researchers have developed an inexpensive, environmentally friendly and safe hydrogen production technology from water. <small>([[Israel#September_13|more]])</small> [[File:Israel.gif]] | |
− | * Indonesia's new parliament elected its first female speaker, Puan Maharani Nakshatra Kusyala, daughter of former president Megawati Sukarnoputri. <small>([[Indonesia#October_1|more]])</small> [[File:Indonesia.gif]] | |
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− | [[File:D_EDITORS_PICKS_192.jpg|240px|left|link=http://news.nus.edu.sg/research/targeting-tumour-producing-cells-liver-cancer|D+ Editor's Pic]] | + | [[File:D_EDITORS_PICKS_193.jpg|240px|left|link=https://www.utoronto.ca/news/u-t-researcher-develops-nanosystem-promotes-regeneration-after-root-canals|D+ Editor's Pic]] |
− | <big>'''NUS researchers show potential liver cancer treatment by targeting cancer stem-like cells'''</big> | + | <big>'''Researcher develops nanosystem that promotes regeneration after root canals'''</big> |
− | <br />Liver cancer is the second leading cause of cancer-related deaths worldwide. The most common primary liver cancer in adults is known as hepatocellular carcinoma (HCC), and accounts for approximately 780,000 deaths every year. Even with advanced surgical treatments or transplantation, the 5-year survival rate for HCC patients remains poor due to frequent recurrence. | + | <br />A novel nanosystem developed by Anil Kishen, a professor in the University of Toronto’s Faculty of Dentistry, shows promising results in promoting healing and regeneration by host tissues following root canals. |
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− | Now, a new study from NUS researchers has demonstrated a potential method for treating advanced liver cancers like HCC. Led by Associate Professor Edward Chow, who is a Principal Investigator with the Cancer Science Institute of Singapore (CSI) at NUS and Dr Toh Tan Boon, who is Head of the Translational Core Laboratory at NUS N.1 Institute for Health (N.1), a team of NUS scientists showed that a class of small molecule drugs that target the JAK/STAT signalling pathway could be used to fight against the disease.
| + | Kishen’s research was published recently in the medical journal Nanomedicine: Nanotechology, Biology and Medicine. |
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− | “Targeting molecular mechanisms that drive chemoresistance has shown success in clinical trials for other diseases. Therefore, such targeted approaches can be potentially useful as adjuvant therapies to improve clinical outcomes of HCC patients,” explained Assoc Prof Chow. <small>([http://news.nus.edu.sg/research/targeting-tumour-producing-cells-liver-cancer More])</small>
| + | The current treatment for root canals focuses on reducing bacterial loads. After instrumentation and irrigation, however, the canals of the tooth are filled with synthetic materials – with the possibility that the infecting bacteria colonies are not fully eliminated. That can leave the tooth susceptible to persistent infections. <small>([https://www.utoronto.ca/news/u-t-researcher-develops-nanosystem-promotes-regeneration-after-root-canals More])</small> |
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