New type of immune cell discovered in breast ducts
Melbourne breast cancer researchers have discovered a new type of immune cell that helps to keep breast tissue healthy by regulating a vital process within mammary ducts – the sites where milk is produced and transported, but also where most breast cancers arise.
Using advanced three-dimensional (3D) imaging techniques, the team observed how the immune cells monitor for threats in the mammary ducts and help to maintain tissue health by ‘eating’ up dying milk-producing cells needing to be cleared away once lactation stops.
The preclinical research was led by Walter and Eliza Hall Institute researchers Dr Caleb Dawson, Professor Geoff Lindeman and Professor Jane Visvader, along with Dr Anne Rios who is now based at the Princess Máxima Center for Pediatric Oncology, Netherlands. (More)