Stanford scientists revise a decades-old model of how proteins move in cells
By using modern techniques to study how proteins are directed to various areas within a cell, Stanford scientists are revising the fundamental understanding of cellular mechanisms. The work could impact future drug designs.
When things are going right in your body, it’s because long strings of brand-new proteins are being folded up into just the right tangles and being delivered to just the right place within the cell at just the right time. Conversely, many human diseases – cancer and neurodegenerative diseases among them – occur because some aspect of this process goes awry.
Understanding the mechanisms that drive these processes is central to designing increasingly effective drugs and therapies for these diseases. (More)